Dog CYP2C21 and dog CYP-reductase coexpressed in Escherichia coli
1 nmol cytochrome P450
50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA
Store at -80°C. Avoid frequent temperature changes. Thaw on ice.
Use: For laboratory (research) purposes only
c Reductase Activity:
P450 Activity Data (1)
with time up to:
with P450 up to:
2.5 pmol/min/pmol CYP
P450 Activity Data (2)
Note:Data obtained over a substrate
concentration range from 40 - 500 µM do not fit to the
The tolbutamide 4-hydroxylase activity of
Bactosomes at 500 µM tolbutamide is approximately 0.2
pmol/min/pmol CYP. This is lower than the activity of CYP2C41LR
Bactosomes at the same substrate concentration.
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under licence from BTG International Ltd (AU730155, EP0914446,
US6566108 and other patents pending).
United States Patent Nos. 5,420,027 or 5,240,831, Canada Patent No.
2100245 and other patents pending.