Human CYP2C8BLR Bactosomes

Catalogue Number: CYP052

Product Description: Human CYP2C8 and human CYP-reductase coexpressed in Escherichia coli and supplemented with purified human cytochrome b₅

Amount: 1 nmol cytochrome P450

Storage Buffer: 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA

Storage: Store at -80°C. Avoid frequent temperature changes. Thaw on ice.

Intended Use: For laboratory (research) purposes only

Note: This product is also available in our convenient EasyCYP format.

Typical Batch Characteristics

P450 Concentration: 6 nmol/ml

Protein Concentration: 12 mg/ml

Cytochrome b₅ Concentration:
      30 nmol/ml

Specific P450 Content:
      500 pmol/mg protein

Cytochrome c Reductase Activity:
      160 nmol/min/mg protein

Typical P450 Activity Data

Activity: Paclitaxel 6a-hydroxylase

Linear with time up to: 15 min

Linear with P450 up to: 60 pmol/ml

Vmax: 1 pmol/min/pmol CYP

Km: 2.5 µM

Product Information Sheets

More Information Available

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Made under licence from BTG International Ltd (AU730155, EP0914446, US6566108 and other patents pending).

United States Patent Nos. 5,420,027 or 5,240,831, Canada Patent No. 2100245 and other patents pending.